INTRODUCTION
1) In context of immune response, Phagocytosis is a component of second line of defense .
2) Cells that perform this function are known as phagocytes.All phagocytes are either WBC or their derivatives.
3) Phagocytes ingest the microorganism and work to destroy them using variety of hydrolytic and other enzymes in a low pH environment.
4) It is highest among Neutrophiles which are WBC followed by macrophages which are derivatives of monocytes (a kind of WBC).
5) During the course of an infection, a shift occurs in the type of WBC that predominates .Neutrophils are the active phagocytes during initial phase of bacterial infections and macrophages predominate both during later phases of bacterial infection and during viral and fungal infections.
PHAGOCYTOSIS IS EXPLAINED IN OUR OTHER BLOG in detail:
PHAGOCYTOSIS :the process
1) In context of immune response, Phagocytosis is a component of second line of defense .
2) Cells that perform this function are known as phagocytes.All phagocytes are either WBC or their derivatives.
3) Phagocytes ingest the microorganism and work to destroy them using variety of hydrolytic and other enzymes in a low pH environment.
4) It is highest among Neutrophiles which are WBC followed by macrophages which are derivatives of monocytes (a kind of WBC).
5) During the course of an infection, a shift occurs in the type of WBC that predominates .Neutrophils are the active phagocytes during initial phase of bacterial infections and macrophages predominate both during later phases of bacterial infection and during viral and fungal infections.
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| A neutrophil cell phagocytosing an antacs bacilli |
PHAGOCYTOSIS :the process
Mechanism of phagocytosis
1) PHAGOCYTOSIS consists of 5 steps:
• Chemotaxis
• Adherence
• Ingestion
• Digestion
• Residual body formation
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| A simple and detailed diagram of phagocytosis |
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